Author Instructions

Manuscript Template.docx

Authors are requested to follow the submission format outlined below to ensure smooth processing and review of manuscripts.

Type of the Paper:
Clearly specify the type of submission—Research Article, Review Article, Short Communication, Case Study, or Methodological Paper.
Title of the Manuscript:
Should not exceed 20 words. Provide a concise, informative title that reflects the content of the manuscript.
Short Title:
A maximum of 7 words for indexing and running headers.
Author Information:
List all author names in the format: Lastname Firstname (Initials are not allowed). ORCID iD is mandatory for all authors.

Example:
Lastname Firstname1 (ORCiD)
Lastname Firstname2 (ORCiD)
Lastname Firstname3*(ORCiD)
Affiliations:
Use superscript numbers to indicate affiliations.

Example:
^¹Department of Marine Biotechnology, AMET University, India
^²Institute of Bioinformatics, XYZ University, USA
Corresponding Author:
Provide full name and official institutional email address of the corresponding author.
Keywords:
Provide 5–6 keywords relevant to the manuscript’s content for indexing.
Graphical Abstract:
Include a high-quality image summarizing the study, with a two-to-three sentence caption explaining the figure.
Major Highlights of the Research:
List 4–5 concise bullet points capturing the novelty and significance of the work.
Abstract:
Submit a clear and structured abstract not exceeding 250 words that summarizes the objectives, methods, key findings, and conclusions.
Manuscript Structure:
Introduction (max. 700 words)
Materials and Methods (max. 1200 words)
Results and Discussion (max. 2100 words)
Conclusion (max. 400 words)
Supplementary Information (if any)
Disclosure Statements (Mandatory):
Author Contributions
Declaration of Generative AI Use
Conflict of Interest Statement

Funding Acknowledgment
IRB/Ethics Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Introduction
The introduction should briefly place the study within a broader scientific context and explain its importance. It should clearly define the purpose of the work and its significance. A concise review of the current state of the research field should be included, citing key publications appropriately. If applicable, highlight any controversial or conflicting hypotheses. Conclude the introduction by stating the primary objective of the study and summarizing the main findings. The introduction should be written in a way that is accessible to scientists outside your specific field of research. References must be numbered in the order of appearance and indicated using square brackets—for example, [1], [2,3], or [4–6].
Kindly note: Introduction should not cross more than 700 words
Materials and Methods
The Materials and Methods section should include sufficient detail to enable others to replicate and build upon the published results. Submission of your manuscript implies that all materials, data, computer code, and protocols associated with the study will be made available to readers. Any restrictions on the availability of these resources must be disclosed at the time of submission. Novel methods and protocols should be described in full, while well-established methods may be summarized and properly cited. For research manuscripts reporting large datasets deposited in publicly accessible databases, please specify the repository and include relevant accession numbers. If accession numbers are not yet available at the time of submission, indicate that they will be provided during the review process. These must be included before publication. For studies involving human or animal subjects or any procedures requiring ethical approval, you must identify the approving authority and provide the corresponding ethical approval code.
Kindly note: Materials and Methods should not cross more than 1200 words
Results and Discussion
This section may be organized using subheadings. It should offer a concise and precise presentation of the experimental results, their interpretation, and the conclusions that can be drawn. The Results section should be followed by a Discussion that interprets the findings in the context of previous studies and the original hypotheses. The implications of the results should be discussed as broadly as possible, emphasizing their relevance to the field. Where appropriate, potential directions for future research may also be highlighted.
Kindly note: Results and Discussion should not cross more than 2100 words
Conclusion
The Conclusion should provide a clear and concise summary of the key findings presented in the Results and Discussion sections. It should articulate the primary conclusions derived from the study and highlight their significance within the broader context of the research field. Rather than repeating earlier content, this section should offer a focused synthesis that underscores the study’s unique contributions to current knowledge. The Conclusion should be well-structured, written in a straightforward manner, and limited to 250–400 words.
Kindly note: Conclusion should not cross more than 400 words
Tables
All tables must be uploaded as individual, editable files (such as Word or Excel) and should not be embedded within the main manuscript document.
Figures
Figures must be submitted as separate, individual files and should not be embedded within the main manuscript text. Each figure should be of high resolution, with a minimum of 300 dots per inch (dpi), to ensure clarity and print quality. Acceptable file formats include TIFF, JPEG, PNG, or EPS. Figures should be prepared in a professional and publication-ready manner, with all graphical elements, labels, and annotations clearly visible and legible. Fonts used in figures should be consistent and large enough to be readable when scaled. Each figure must include a corresponding figure legend, provided either within the figure file or in a separate legends document, clearly explaining the content and context. Please ensure that figures are accurately numbered and referenced appropriately within the text. If any figures include previously published material, proper permissions must be obtained and documented.
Supplementary Information’s
Supplementary materials should be referenced appropriately within the main manuscript. If the supplementary data include large datasets, video files, or software code, ensure they are submitted in universally accessible formats and accompanied by adequate documentation or usage notes. Please ensure that all supplementary content complies with the journal’s data availability and reproducibility policies.
Author Contributions
For articles with multiple authors, a brief paragraph outlining each author's specific contributions must be included. The following standardized format should be used: “Conceptualization, X.X. and Y.Y.; Methodology, X.X.; Software, X.X.; Validation, X.X., Y.Y., and Z.Z.; Formal Analysis, X.X.; Investigation, X.X.; Resources, X.X.; Data Curation, X.X.; Writing—Original Draft Preparation, X.X.; Writing—Review and Editing, X.X.; Visualization, X.X.; Supervision, X.X.; Project Administration, X.X.; Funding Acquisition, Y.Y.”
All authors must confirm that they have read and approved the final version of the manuscript.
Please refer to the CRediT (Contributor Roles Taxonomy) for definitions of each role. Authorship should be restricted to individuals who have made significant and meaningful contributions to the research and manuscript preparation.
Declaration of Generative AI and AI-Assisted Technologies in the Writing Process
Authors must disclose whether generative AI tools (e.g., ChatGPT, Bard) or other AI-assisted technologies were used in the preparation of the manuscript. If such tools were employed, authors should specify the tool used, the purpose (e.g., language editing, summarization, idea generation), and the extent of its contribution. Authors remain fully responsible for the content of the manuscript, including the accuracy, originality, and integrity of all statements.

For example, a suitable disclosure might be: “Portions of the text were edited for language clarity using ChatGPT (OpenAI), under the direct supervision of the authors.”
If no AI tools were used, authors should explicitly state: “No generative AI or AI-assisted technologies were used in the writing or editing of this manuscript.”
This declaration is required to ensure transparency and uphold the ethical standards of scientific publishing.
Funding Information
All sources of financial support for the research must be clearly acknowledged. Please include the full name of the funding organization(s), grant numbers (if applicable), and the recipients of each grant. For example: “This work was supported by the National Science Foundation [Grant No. 123456] awarded to A.B.”
If the research did not receive any specific funding, authors should state: “This research received no external funding.”
Accurate disclosure of funding is essential for transparency and compliance with institutional and publisher policies.
Institutional Review Board Statement
All studies involving humans or animals must include a statement regarding ethical approval. Authors should clearly indicate the name of the institutional review board or ethics committee that approved the study, along with the approval number and date. For example:
“The study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board of [Institution Name] (Approval No. XXX, Date: DD/MM/YYYY).”

If the study did not require ethical approval (e.g., due to the use of publicly available data or exemption by the IRB), please state:
“Ethical review and approval were waived for this study by the Institutional Review Board of [Institution Name], as the research involved publicly available data.”
or
“This study did not require ethical approval in accordance with the guidelines of [Institution Name] and applicable national regulations.”
Accurate and transparent reporting of ethical oversight is required for publication.
Informed Consent Statement
For all studies involving human participants, a statement confirming informed consent must be included. Authors should specify that participants provided voluntary, written (or oral, where appropriate) informed consent in accordance with institutional and ethical guidelines. For example:
“Informed consent was obtained from all subjects involved in the study.”
or
“Written informed consent was obtained from all participants prior to their inclusion in the study.”
If informed consent was waived or not required, please provide a justification approved by the relevant ethics committee. For example:
“Patient consent was waived by the Institutional Review Board of [Institution Name] due to the retrospective nature of the study and use of anonymized data.”
In studies involving minors or vulnerable populations, include a statement indicating that consent was obtained from legal guardians or representatives, as applicable.
If study not involved any of these, mention not applicable.
Clear documentation of informed consent is essential for maintaining ethical research standards and ensuring compliance with publication requirements.
Data Availability Statement
Authors must provide a clear statement regarding the availability of the data supporting the findings of the study. If the data are publicly available, please specify the repository and include relevant accession numbers or DOIs. For example:
“The data presented in this study are openly available in [Repository Name] at [DOI or URL], reference number [accession number].”
If the data are not publicly available but can be shared upon request, please state: “The data that support the findings of this study are available from the corresponding author upon reasonable request.”
If there are restrictions on data availability due to privacy, ethical, or legal concerns, please indicate: “The data are not publicly available due to [reason, e.g., participant privacy or institutional policy].”
If no new data were generated or analyzed, state: “No new data were created or analyzed in this study.”
Transparent reporting of data availability ensures reproducibility and supports open science practices.
Acknowledgments
Authors should use this section to recognize individuals, organizations, or institutions that contributed to the work but do not meet the criteria for authorship. This may include those who provided technical assistance, administrative support, access to facilities, or critical feedback. For example: “The authors thank Dr. XXYYXX XXYYXX for his/her assistance with data analysis and the XYZ Laboratory for providing access to research equipment.”
If applicable, acknowledge funding bodies separately under the Funding section and avoid duplication here. If there are no acknowledgments, please state:
“The authors would like to acknowledge that there are no additional contributions to report.”
This section reflects professional courtesy and transparency in recognizing collaborative efforts.
Conflicts of Interest:
All authors must disclose any potential conflicts of interest that could be perceived to influence the results or interpretation of the manuscript. This includes financial relationships (e.g., funding, employment, stock ownership, honoraria), personal relationships, academic competition, or intellectual beliefs that may affect objectivity.
If there are no conflicts to declare, please state:
“The authors declare no conflict of interest.”
If a potential conflict exists, clearly disclose the nature of the relationship. For example:
“Author A has received research funding from Company X. Author B is a consultant for Company Y.”
Full disclosure ensures transparency and maintains the integrity of the scientific record.
Reference
All references cited in the manuscript must be listed at the end of the document and formatted consistently according to the journal’s required citation style. Authors are strongly encouraged to use reference management software such as EndNote, Reference Manager, Zotero, or Mendeley to streamline citation formatting, minimize typographical errors, and prevent duplication.

References should be listed alphabetically by the first author's last name and cited appropriately within the text (e.g., Singh et al., 2025), in line with the journal’s in-text citation guidelines. Each reference entry must include complete bibliographic details: all author names, year of publication, full article title, journal name (italicized or styled per journal requirements), volume number, issue (if applicable), page range, and the Digital Object Identifier (DOI).

DOIs must be included for all references where available, as they provide a stable and permanent link to the source material.

Ensure that all in-text citations correspond accurately to entries in the reference list and that all listed references are cited in the manuscript. References to unpublished data, personal communications, or manuscripts under review should not be included in the reference list but may be cited within the text with appropriate context and permissions.

Example Reference:
Singh, A., M. Bakhtyar, S. R. Jun, M. Boerma, R. S. Lan, L. J. Su, S. Makhoul, and P. C. Hsu. 2025. "A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity." Metabolomics 21 (3):68. doi: 10.1007/s11306-025-02258-8.

For EndNote users, the corresponding EndNote style file is attached (Click Here). Authors using EndNote are encouraged to submit the .enl and .xml files along with their manuscript submission to ensure accurate formatting.
Disclaimer / Publisher’s Note
The views, opinions, conclusions, and data expressed in all articles and other content published are solely those of the respective author(s) and contributor(s) and do not necessarily reflect the views of Aayvu Publications Pvt. Ltd., the editors, or affiliated institutions. The publisher and editors make no representations or warranties, express or implied, regarding the accuracy, completeness, or validity of the content.

Aayvu Publications Pvt. Ltd. and/or the editorial team accept no responsibility for any errors, omissions, or consequences arising from the use of information, methodologies, instructions, or products discussed in the published material. The publisher expressly disclaims liability for any loss, damage, or injury to persons or property that may result from the application or implementation of any ideas, procedures, or products described in the publication.

Authors bear full responsibility for the content they submit, including obtaining necessary ethical approvals, permissions, and conflict of interest disclosures. It is the responsibility of the reader to independently evaluate the appropriateness and safety of any content before relying on it.

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