RESEARCH PAPER
Antibacterial activity of Moringa oleifera, Solanum nigrum, and Sesbania grandiflora against Bacteria isolated from wound infections
1
PG & Research Department of Biotechnology and Bioinformatics, Holy Cross College (Autonomous), Affiliated to Bharathidasan University, Tiruchirappalli, India.
2
Department of Microbiology, K.A.P Viswanatham Govt Medical College, Tiruchirappalli, India.
Submission date: 2025-09-21
Final revision date: 2025-11-18
Acceptance date: 2025-12-07
Online publication date: 2026-01-28
Publication date: 2026-01-28
Journal of Medico Informatics 2026;2(1):12-16
HIGHLIGHTS
- Medicinal plant extracts showed antibacterial activity against wound infection bacteria.
- Ethanol extracts exhibited higher antibacterial activity due to phytochemical compounds.
- Solanum nigrum demonstrated strongest antibacterial activity among tested medicinal plants.
- Antibacterial activity increased with extract concentration in agar diffusion assays.
- Plant-derived compounds may serve as alternative antimicrobial agents against resistant bacteria.
KEYWORDS
TOPICS
ABSTRACT
Around the world, most of the medical systems usually employ medicinal herbs to treat both acute and chronic wounds. The current study aims to evaluate the antibacterial properties of Moringa oleifera, Solanum nigrum, and Sesbania grandiflora. These plants were tested for antibacterial activity against wound infections by collecting and extracting the plant’s crude material. By using the Hanging drop method and the agar-well diffusion method, three distinct bacterial colonies were identified. Ethanol extract showed the most significant antibacterial activity, attributed to the presence of alkaloids, tannins, saponins, phenols, and steroids. The antibacterial activity varied for different test samples of 500 µg/ml, with the positive control serving as a reference of the expected effect. Solanum nigrum's potent antibacterial properties suggest its potential as a valuable natural resource in combating bacterial diseases, potentially aiding in future herbal medicine and pharmaceutical research. The results suggest these plants could be valuable natural resources for combating bacterial diseases.
ACKNOWLEDGEMENTS
The authors thankfully acknowledge the Department of Science and Technology, Government of India, for providing support through the Fund for Improvement of S&T Infrastructure in Universities and Higher Educational Institutions (FIST) program (Grant No. SR/FIST/College /2020/943).
FUNDING
Department of Science and Technology, Government of India, through the Fund “Improvement of S&T Infrastructure in Universities and Higher Educational Institutions (FIST) program (Grant No. SR/FIST/College /2020/943)”
CONFLICT OF INTEREST
The authors declare that they have no known financial, personal, academic, or other relationships that could inappropriately influence, or be perceived to influence, the work reported in this manuscript. All authors confirm that there are no competing interests to declare.
PEER REVIEW INFORMATION
Article has been screened for originality
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